Publications 2017

  • Sulfoximines from a Medicinal Chemist’s Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery
    M. Frings, C. Bolm, A. Blum, C. Gnamm, Eur. J. Med. Chem. 2017, 126, 225–245.
  • Altering Product Selectivity by Mechanochemistry
    J. G. Hernández, C. Bolm, J. Org. Chem. 2017, 82, 4007–4019.
  • Access to N-cyanosulfoximines by transition metal-free iminations of sulfoxides
    C. A. Dannenberg, L. Fritze, F. Krauskopf, C. Bolm, Org. Biomol. Chem. 2017, 15, 1086–1090.
  • Rhodium(III)-Catalyzed Annulation of N-Methoxybenzamides with Heterobicyclic Alkenes by C–H Functionalization: Synthesis of Benzo[b]phenanthridinones
    Y. Cheng, K. Parthasarathy, C. Bolm, Eur. J. Org. Chem. 2017, 1203–1206.
  • Mechanochemical Lignin-Mediated Strecker Reaction
    S. Dabral, M. Turberg, A. Wanninger, C. Bolm, J. G. Hernández, Molecules 2017, 22, 146.
  • Rhodium(III)-Catalyzed Ortho Halogenations of N-Acylsulfoximines and Synthetic Applications toward Functionalized Sulfoximine Derivatives
    Y. Cheng, W. Dong, K. Parthasarathy, C. Bolm, Org. Lett. 2017, 19, 726–729.
  • 1,2-Benzothiazines from Sulfoximines and Allyl Methyl Carbonate by Rhodium-Catalyzed Cross-Coupling and Oxidative Cyclization
    J. Wen, D. P. Tiwari, C. Bolm, Org. Lett. 2017, 19, 1706–1709.
  • Mechanochemical indole synthesis by rhodium-catalysed oxidative coupling of acetanilides and alkynes under solventless conditions in a ball mill
    G. N. Hermann, C. L. Jung, C. Bolm, Green Chem. 2017, 19, 2520–2523.
  • Mechanoenzymatic peptide and amide bond formation
    J. G. Hernández, K. J. Ardila-Fierro, D. Crawford, S. L. James, C. Bolm, Green Chem. 2017, 19, 2620–2625.
  • Sulfoximines as ATR inhibitors: Analogs of VE-821
    C. M. M. Hendriks, J. Hartkamp, S. Wiezorek, A.-D. Steinkamp, G. Rossetti, B. Lüscher, C. Bolm, Bioorg. Med. Chem. Lett. 2017, 27, 2659–2662.
  • Mechanochemical Rhodium(III)-Catalyzed C–H Bond Amidation of Arenes with Dioxazolones under Solventless Conditions in a Ball Mill
    G. N. Hermann, C. Bolm, ACS Catal. 2017, 7, 4592–4596.
  • Design, Synthesis and Evaluation of N-(tert-butyl)-Alanine-Derived Chiral Ligands – Aspects of Reactivity and Diastereoselectivity in the Reactions with α-Amino Acids
    M. Bremerich, C. Bolm, G. Raabe, V. Soloshonok, Eur. J. Org. Chem. 2017, 3211–3221.
  • Organocatalytic Chemoselective Primary Alcohol Oxidation and Subsequent Cleavage of Lignin Model Compounds and Lignin
    S. Dabral, J. G. Hernández, P. C. J. Kamer, C. Bolm, ChemSusChem 2017, 10, 2707–2713.
  • Dibenzothiophene Sulfoximine as NH3 Surrogate in the Synthesis of Primary Amines by Copper-Catalyzed C–X and C–H Bond Amination
    Z. Li, H. Yu, C. Bolm, Angew. Chem. 2017, 129, 9660–9663; Angew. Chem. Int. Ed. 2017, 56, 9532–9535.
  • Rhodium-catalyzed Synthesis of 1-(Acylamino)isoquinolines through Direct Annulative Coupling of 3-Aryl-1,2,4-oxadiazoles with Alkynes
    Y. Nishii, A.-K. Bachon, S. Moon, C. Bolm, M. Miura, Chem. Lett. 2017, 46, 1347–1349.
  • Organic Dye-Catalyzed Atom Transfer Radical Addition–Elimination (ATRE) Reaction for the Synthesis of Perfluoroalkylated Alkenes
    D. P. Tiwari, S. Dabral, J. Wen, J. Wiesenthal, S. Terhorst, C. Bolm, Org. Lett. 2017, 19, 4295–4298.
  • Selective enzymatic esterification of lignin model compounds in the ball mill
    U. Weißbach, S. Dabral, L. Konnert, C. Bolm, J. G. Hernández, Beilstein J. Org. Chem. 2017, 13, 1788–1795.
  • Synthesis of N-Propargylsulfoximines by Copper-Catalyzed A3-Couplings
    H. Cheng, J. Wen, C. Bolm, Chem. Eur. J. 2017, 23, 12100–12103.
  • Organocatalytic Asymmetric Synthesis of trans-γ-Lactams
    S. Dong, M. Frings, D. Zhang, C. G. Daniliuc, H. Cheng, C. Bolm, Chem. Eur. J. 2017, 23, 13888–13892.
  • Copper-Catalyzed C(sp2)–S Coupling Reactions for the Synthesis of Aryl Dithiocarbamates with Thiuram Disulfide Reagents
    Z.-B. Dong, X. Liu, C. Bolm, Org. Lett. 2017, 19, 5916–5919.
  • Rhodium-Catalyzed [4 + 3] Annulations of Sulfoximines with α,β-Unsaturated Ketones Leading to 1,2-Benzothiazepine 1-Oxides
    J. Wen, H. Cheng, G. Raabe, C. Bolm, Org. Lett. 2017, 19, 6020–6023.
  • Mechanistic Investigation of the Catalyzed Cleavage for the Lignin β-O-4 Linkage: Implications for Vanillin and Vanillic Acid Formation
    T. Rinesch, J. Mottweiler, M. Puche, P. Concepción, A. Corma, C. Bolm, ACS Sustainable Chem. Eng. 2017, 5, 9818–9825.
  • Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification
    G. Karpel-Massler, R. E. Kast, M. D. Siegelin, A. Dwucet, E. Schneider, M.-A. Westhoff, C. R. Wirtz, X. Y. Chen, M.-E. Halatsch, C. Bolm, Neurochem. Res. 2017, 42, 3382–3389.
  • Sulfoximidoyl-Containing Hypervalent Iodine(III) Reagents: 1-Sulfoximidoyl-1,2-benziodoxoles
    H. Wang, D. Zhang, H. Sheng, C. Bolm, J. Org. Chem. 2017, 82, 11854–11858.
  • Mechanochemical Ruthenium-Catalyzed Hydroarylations of Alkynes under Ball-Milling Conditions
    H. Cheng, J. G. Hernández, C. Bolm, Org. Lett. 2017, 19, 6284–6287.
  • Microwave-Assisted Synthesis of Heterocycles by Rh(III)-Catalyzed Annulation of N-Methoxyamides with α-Chloroaldehydes
    J.-R. Huang, C. Bolm, Angew. Chem. 2017, 129, 16137–16141; Angew. Chem. Int. Ed. 2017, 56, 15921–15925.
  • An Iodine-Mediated Hofmann-Löffler-Freytag Reaction of Sulfoximines Leading to Dihydroisothiazole Oxides
    D. Zhang, H. Wang, H. Cheng, J. G. Hernández, C. Bolm, Adv. Synth. Catal. 2017, 359, 4274–4277.